top of page
Knee osteoarthritis


Knee Osteoarthritis and Ultrasound-guided Platelet Rich Plasma Injections

The most common osteoarthritic joint targeted with platelet rich plasma injections is the knee. The knee is asynovial joint where two bones meet and are surrounded by a capsular ligament which provides stability to the joint. The articular surfaces of the bone are made of hyaline cartilage which is made up of a type of collagen. Synovial fluid, which is secreted from the inside lining of the capsule, provides nourishment and lubrication to poorly vascularized joints. Because the hyaline cartilage has a very limited ability to heal due to poor blood flow, osteoarthritis is a common joint disorder. The process of osteoarthritis can be caused by a single trauma or multiple microtraumas to the hyaline cartilage.


In recent years there has been a surge of positive and promising evidence regarding the use of platelet rich plasma injections for the treatment of knee osteoarthritis pain and dysfunction. The exact mechanism of action of platelet rich plasma is not known, but it is known that the synovium changes from an anabolic to a catabolic states, which in turn decreases the pro-inflammatory markers in your knee that keeps sending pain signals to your brain.


At our clinic, we utilize the ultrasound-guidance for added accuracy and safety. This mean that we can visualize exactly the best place for the injection to occur.  Beyond the basic intra-articular injection into the knee, we also examine and treat the extra-articular (ie: ligamentous) potential pain generating structures. Combined with rehabilitation exercises, it is our experience that you will have an enhanced positive outcome.

Platelet-rich plasma in osteoarthritis treatment: review of current evidence, 2019

Platelet rich plasma research with MRI pre and post treatment, 2020 

PRP vs Hyaluronic Acid Injection for Knee Osteoarthritis, 2019

PRP and MRI findings pre and post injections, 2020


bottom of page